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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Novel Therapeutic Targets for Antiarrhythmic Drugs ： ウィキペディア英語版 Novel Therapeutic Targets for Antiarrhythmic Drugs ''Novel Therapeutic Targets for Antiarrhythmic Drugs'' is a book edited by George Billman and published by John Wiley and Sons in 2010. ==Content== According to the publisher, the book describes the current state of cardiac arrhythmia treatment, and attempts to identify future directions research may take.〔(【引用サイトリンク】publisher=John Wiley and Sons )〕 Its 21 chapters cover a variety of topics related to cardiac arrhythmia and electrophysiology, primarily reviewing known molecular targets for drugs.〔 Subjects covered in the book include both traditional approaches to looking at arrhythmia, such as ion channel effects, and more general issues such as the genetics behind differential response to existing drug therapies.〔 Drug safety and side effects are also cover.〔 The book examines avenues by which new treatments might be developed, with four chapters (10, 13, 16, 17) specifically focused on novel targets.〔 Novel ideas offered included studying sodium-calcium exchanger and ryanodine receptor effects.〔 One chapter (5) is dedicated to examining the targets on which existing drugs operate, and another (8) examines drugs in clinical trial at the time of publication. The chemical structure of existing drugs is not covered.〔 Overall, the book advocates for segregating drug targets by disease type and state, rather than the conventional approach of segregating by likelihood to harm.〔 In addition to pharmacological therapies, the book examines potential alternate treatments to arrhythmia including the effect of endurance training on susceptibility. It also investigates omega-3 fatty acids which have a proven effect on cardiac electrophysiology, but have failed to prove protective when obtained through diet.〔 According to cardiologist Peter R. Kowey, the chapter authors are "eminent scientists" in their respective areas.〔 The list includes "some brilliant industry scientists", but does not include any clinicians or drug trialists, possibly creating a biased perspective, according to Kowey. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Novel Therapeutic Targets for Antiarrhythmic Drugs」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.